Do you wake up feeling drained, no matter how long you sleep? Everyday tasks take more effort than they should, and your once-sharp focus fades under a constant sense of exhaustion. After countless tests and appointments, there’s still no clear explanation. For many living with chronic fatigue syndrome, this experience is all too familiar. In this blog, we’ll look at how hormones can affect your energy levels and what to discuss with an endocrinologist if fatigue has become a part of your daily life.
What Is Chronic Fatigue Syndrome?
According to the Centers for Disease Control and Prevention (CDC), CFS is a complex multisystem disease characterized by severe fatigue, cognitive dysfunction, sleep problems, and a worsening of symptoms following physical or mental activity. The condition isn’t simply feeling tired; it represents a profound exhaustion that doesn’t improve with rest. It significantly impacts your ability to perform activities you previously managed without difficulty.
The condition can affect people of all ages, though it’s more common in women than in men. This gender disparity has led researchers to investigate hormonal factors as potential contributors to CFS development and progression.
Hormones and CFS
Hormones play a key role in how the body manages energy, stress, and recovery: all areas that can be disrupted in chronic fatigue syndrome (CFS). People with CFS may have irregularities in the hypothalamic-pituitary-adrenal (HPA) axis, which controls the release of stress hormones such as cortisol. When this system underperforms, it can lead to lower energy levels, poor stress response, and worsened fatigue.
Other hormonal imbalances may also contribute to symptoms. Changes in thyroid, estrogen, or testosterone levels can affect metabolism, sleep, and mood, while fluctuations in growth hormone may impact muscle repair and overall stamina. Though hormone irregularities don’t cause CFS directly, identifying and treating them can help restore balance.
Can Hormonal Treatments Ease CFS?
Hormonal treatments are sometimes explored as a way to ease symptoms of Chronic Fatigue Syndrome (CFS), since many people with the condition show irregularities in how their bodies regulate hormones. However, if hormonal treatment is being considered, it should be pursued only under the supervision of an experienced endocrinologist within a care plan that also addresses lifestyle, sleep, nutrition, and activity planning.
It’s important to understand that CFS and hormonal disorders can coexist. Having one doesn’t exclude the other, and addressing underlying hormonal imbalances may improve your energy, cognitive function, and overall quality of life even if CFS remains present.
What to Expect During Endocrine Evaluation
If you suspect hormonal imbalances may be contributing to your chronic fatigue, a comprehensive endocrine evaluation can be your next step. Here’s what you can expect:
- Detailed Medical History: Your endocrinologist will ask about the onset and pattern of your fatigue, associated symptoms, menstrual history (for women), stress levels, sleep quality, dietary habits, medications, family history of hormonal or autoimmune conditions, and previous evaluations or treatments you’ve tried.
 - Physical Examination: A thorough exam can identify physical signs of hormonal disorders, such as thyroid enlargement, abnormal reflexes, skin changes, blood pressure abnormalities, or other findings that suggest specific endocrine conditions.
 - Comprehensive Laboratory Testing: Blood tests should evaluate multiple hormone systems, including thyroid function, cortisol levels, sex hormones, vitamin D, vitamin B12, complete blood count, comprehensive metabolic panel, and markers of inflammation or autoimmune activity.
 
Looking for an Endocrinologist in Oxon Hill?
If you’re struggling with chronic fatigue that hasn’t responded to conventional treatments, an endocrine evaluation may provide the clarity you need. At Hilltop Endocrinology, we diagnose and treat complex hormonal disorders.
We understand how isolating and frustrating chronic fatigue can feel, especially when you’re searching for answers. Our practice offers flexible appointment options at our convenient Oxon Hill location. We accept patients with private insurance, Medicare, and self-pay options, ensuring that financial concerns don’t prevent you from accessing specialized care.
Dr. Folawewo takes time to listen carefully, explain medical concepts clearly, and develop a comprehensive treatment plan. Contact us today at (301) 567-9570 to schedule your evaluation.

                    

